Staff have reported TVs, toasters and microwaves being unplugged sporadically at the former Saxony Motor Inn, now a Howard Johnson Hotel, 15540 Stony Plain Rd.
Unexplained footsteps in stairwells and bangs on the doors have also been heard.
The strange events have piqued the interest of a local ghost hunter, who's launched a paranormal investigation at the inn.
After speaking with several chambermaids and guests, Sean Seerey, a veteran tarot card reader and hospitality consultant at the hotel, did a late-night reading in a second-floor suite.
While he did the reading, Seerey said the room became so cold he could see his breath.
"It was 23 or 24 degrees outside that night and I could see my breath (in the room)," said Seerey, 45.
The Saxony was a posh 40-room Spanish-style hotel when it opened in 1966.
But over the years, its high-class facade crumbled.
In the 1980s a strip club operated at the inn and later, a bingo hall.
On Dec. 21, 1990, Lorraine Wray, a 46-year-old masseuse, was found strangled in the bathroom of her business, a massage studio in a strip mall attached to the hotel.
"Spirits are either lost or they're observing something or they've got an agenda they need to accomplish before they move on," said Seerey.
While walking through the halls during late shifts, Seerey says he felt a spirit move through his body. He says he's also smelled rose perfume.
Front desk manager Debbie Hart says longtime staff members speak of a trick-playing spirit named Bob who lives at the hotel.
Over the years at the hotel, staff recall lights flickering in the lounge, footsteps in the stairwell when no one is there, and knocks on doors.
"The older staff say it's Bob playing again," said Hart.
Hotels are hotspots for hauntings, said Barbara Smith, author of four Ghost Stories of Alberta books.
"Hauntings seem to be connected with strong emotion which is a form of energy," said Smith.